YLS-8B Small Animal Nebulizer Introduction: There are currently two types of medical nebulization devices available on the market for animal experiments: one is jet nebulization, and the other is ultrasonic nebulization, but both of these nebulization devices have their own insurmountable shortcomings. The pneumatic spray device is difficult to achieve consistency and accuracy due to the influence of multiple factors such as air pressure, air hole, airway, etc. The biggest problem with existing ultrasonic nebulizers is the generation of high temperatures, which alter the activity of drugs (such as corticosteroids and proteins) and limit their range of use. We have conducted intensive research on this and discovered a new type of ultrasonic microporous atomization device that can overcome the shortcomings of the current two atomization devices. This device is different from previous ultrasonic atomizers in that it does not rely on ultrasonic vibration to form the "cavitation effect" of the liquid, allowing the droplets to overcome surface tension and escape. We know that the "cavitation effect" generates high temperature and high pressure, and its impact on drugs is inevitable, which is why ultrasonic nebulizers cannot dry burn. The working principle of the atomization device we are currently using is to use an ultrasonic diaphragm as a pump, which vibrates and sprays the liquid on one side of the diaphragm through horn shaped micropores from the other side. The size of the micropores determines the fineness of the droplets. During the spraying process, the liquid carries away the heat generated by vibration, so it does not produce high temperature and high pressure (can operate without water), thus overcoming the defects of the original ultrasonic atomization. We fully utilized this advantage of the device and developed a small animal nebulization drug delivery device. characteristic: 1. Fine atomized particles (1-5 μ m accounting for 80%) can smoothly enter the alveoli. 2. It can perform real-time standard calibration of atomization volume after using different liquids or replacing the atomization head. 3. Able to use boxes of different volumes or administer nasal inhalation to individually housed animals. 4. It is convenient to add medication, clean, replace animal containers, and atomizer heads. 5. It has a filtering exhaust system and manual counting of cough sounds, as well as recording of the first cough sound time (incubation period) function. 6. Adopting a dual channel design and a touch sensitive LCD screen display, it has a good human-machine dialogue interface and can be connected to a computer to read data. The operation is simple and convenient. Technical parameters: Fineness of atomized particles: 1-5 μ m (accounting for 80%) Atomization head size: Φ26×30mm Animal box: Container size large: 10L 305 × 260 × 170mm (optional) medium size 8L 285 × 240 × 160mm (optional) Small Number: 5L 255 × 210 × 135mm (standard) The maximum dosage of the atomizing head at once: 1ml Atomization dosage during calibration: 0.1-1ml. Set the step size to 0.1ml (the larger the calibrated atomization dosage, the more accurate it is) Test time setting: 0-240 minutes, set step size to 1 minute (0 is no time set) Spray volume setting: 0.1-60ml Set the step size as 0.1ml
Introduction: There are currently two types of medical nebulization devices available on the market for animal experiments: one is jet nebulization, and the other is ultrasonic nebulization, but both of these nebulization devices have their own insurmountable shortcomings. The pneumatic spray device is difficult to achieve consistency and accuracy due to the influence of multiple factors such as air pressure, air hole, airway, etc. The biggest problem with existing ultrasonic nebulizers is the generation of high temperatures, which alter the activity of drugs (such as corticosteroids and proteins) and limit their range of use. We have conducted intensive research on this and discovered a new type of ultrasonic microporous atomization device that can overcome the shortcomings of the current two atomization devices. This device is different from previous ultrasonic atomizers in that it does not rely on ultrasonic vibration to form the "cavitation effect" of the liquid, allowing the droplets to overcome surface tension and escape. We know that the "cavitation effect" generates high temperature and high pressure, and its impact on drugs is inevitable, which is why ultrasonic nebulizers cannot dry burn. The working principle of the atomization device we are currently using is to use an ultrasonic diaphragm as a pump, which vibrates and sprays the liquid on one side of the diaphragm through horn shaped micropores from the other side. The size of the micropores determines the fineness of the droplets. During the spraying process, the liquid carries away the heat generated by vibration, so it does not produce high temperature and high pressure (can operate without water), thus overcoming the defects of the original ultrasonic atomization. We fully utilized this advantage of the device and developed a small animal nebulization drug delivery device.
