Introduction: The pilot50 preparative liquid chromatography is a typical preparative chromatography system. Although it has a width of less than 30 cm and a small volume, it has a large preparation capacity. The pilot series of preparative liquid chromatography and high pressure preparative liquid chromatography adopt modular design, powerful functions and simple system operation, allowing the use of gradient elution of up to 4 different solvents, simultaneous online detection of two wavelengths, and easy storage and recall of methods , And can complete the fraction collection work under the same platform, support the system connection of stainless steel chromatography column and high-pressure glass chromatography column, widely used in the separation and purification of target active ingredients such as Chinese herbal medicine, natural products, organic synthesis products and protein biopolymers. Preparation, from laboratory research to industrial production, can meet its requirements. Features: 1. It can quickly complete the purification and preparation of small molecule and macromolecular active ingredient compounds 2. Highly flexible modular configuration, integrated fraction collection, making the scientific research process more intuitive 3. Cam curve compensation technology effectively controls flow pulsation and ensures low baseline noise 4. Multi-point flow calibration curve to ensure flow accuracy and system repeatability within the full flow range 5. The pump head has an automatic cleaning function to avoid buffer residue and crystal precipitation Simultaneous detection of dual wavelengths in the range of 190-800nm, reliable online analysis of main components, by-products and impurities 7. Convenient replacement of lamps and flow cells, intelligent switching of deuterium lamps and tungsten lamps, to ensure maximum operating time 8. High-sensitivity online detection, the system supports optional UV, ELSD, RI and other detectors 316L stainless steel, PEEK, pure titanium, Hastelloy, a variety of materials to choose from 10. Fully automatic fraction collector, with multiple collection modes, can be configured with multiple specifications of collection tubes 11. Project management adopts database mode to manage data, and the instrument methods, spectrum data, and analysis methods associated with the project are all stored under the project 12. Strict authority management, electronic records, electronic signatures, audit trail functions, implementation of user registration and multiple authority setting methods 13. The system control software fully complies with CFDA GxP and FDA 21CFR Part11 regulatory requirements 14. The system can be adapted to connect with any brand of chromatographic column, SPE solid phase extraction column Technical Parameters: Pump head: 316L stainless steel pump, high precision, low pulse, corrosion resistance (peek pump head optional) Flow rate range: 0.01-50.00ml/min (gradient) Flow rate accuracy: ±0.5% Pressure range: 0-30MPa Pressure pulsation: ≤0.2MPa Gradient type: step, linear change gradient, gradient and flow rate can be modified online Minimum gradient adjustment: 1% Detector light source: deuterium lamp + tungsten lamp (imported) Detection wavelength: 190-800nm full-wavelength detector, dual-wavelength simultaneous detection Wavelength accuracy: ±1nm Absorbance range: 0-2AU Collection: automatic collector Collection tube rack: 2×60 test tubes (Φ15mm*150mm test tubes) Other specifications can be optional Collection mode: normal mode (time collection, peak collection, threshold collection), sequential collection, circular collection Manual loading valve: Preparative chromatography valve (standard 10ml loop) Sample loading method: solid loading or liquid loading Power supply: 220V±10% 50Hz
Introduction: The pilot50 preparative liquid chromatography is a typical preparative chromatography system. Although it has a width of less than 30 cm and a small volume, it has a large preparation capacity. The pilot series of preparative liquid chromatography and high pressure preparative liquid chromatography adopt modular design, powerful functions and simple system operation, allowing the use of gradient elution of up to 4 different solvents, simultaneous online detection of two wavelengths, and easy storage and recall of methods , And can complete the fraction collection work under the same platform, support the system connection of stainless steel chromatography column and high-pressure glass chromatography column, widely used in the separation and purification of target active ingredients such as Chinese herbal medicine, natural products, organic synthesis products and protein biopolymers. Preparation, from laboratory research to industrial production, can meet its requirements.
